The overall objective of the Neonatal Neuroprotection group is to identify and evaluate novel neuroprotective interventions to improve development and health in extremely vulnerable clinical populations.
From a clinical perspective, our research focus on three main groups of infants:
- Infants born extremely preterm,
- Infants who develop severe cerebral intraventricular hemorrhage, and
- Infants with severe congenital heart defects requiring surgery assisted by cardiopulmonary bypass
Through our research, we aim to:
- Build an increased understanding of the processes responsible for the development of brain damage and subsequent neurological and cognitive impairment
- Identify novel protective treatment strategies in order to improve neurodevelopment
We are pleased to share that our research group is collaborating with Spädbarnsfonden. This partnership marks a significant step in our ongoing efforts to contribute to vital research in neonatal care and development.
For more information about Spädbarnsfonden, please visit: https://www.spadbarnsfonden.se/forskningsnamnden/
In a recent interview by the Faculty of Medicine at Lund University, our researchers Niklas Ortenlöf and Magnus Gram discuss their research related to Niklas’s doctoral thesis, shedding light on important aspects of neonatal brain development.
Read the full interview here: https://www.medicin.lu.se/artikel/viktig-transportvag-i-den-omogna-hjarnan-hos-tidigt-fodda
Evaluation of recombinant human IGF-1/IGFBP-3 on intraventricular hemorrhage prevention and survival in the preterm rabbit pup mode
Authors: Claes Ekström, Niklas Ortenlöf, Amanda Kristiansson, Bo Holmqvist, Åsa Jungner, Suvi Vallius, Xiaoyang Wang, Ann Hellström, Norman Barton, Galen Carey, David Ley & Magnus Gram. Biomolecules. 2023;13, 19847
Full text: https://www.nature.com/articles/s41598-023-46611-0?utm_source=rct_congratemailt&utm_medium=email&utm_campaign=oa_20231114&utm_content=10.1038/s41598-023-46611-0